Endothelium-dependent relaxation of internal mammary artery produced by resveratrol
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چکیده
منابع مشابه
Dyslipidemia and endothelium-dependent relaxation in internal mammary arteries used for coronary bypass surgery.
OBJECTIVE Impairment of endothelium-dependent relaxation is related to dyslipidemia and may be an early marker for atherosclerosis in angiographically smooth arteries. The aim of the present study was to relate preoperative serum lipids to endothelium-dependent relaxation in internal mammary arteries of patients undergoing coronary bypass surgery. METHODS The study group consisted of 37 patie...
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The internal mammary artery (IMA) is currently the preferred conduit for myocardial revascularization. However, pre-operative vasospasm and a hypoperfusion state during maximal exercise may limit its use as a bypass graft. The mechanism of spasm has not been clearly defined. Since β-adrenoceptor activation plays a major role in vasorelaxation, the present study was carried out to investigate th...
متن کاملDoes potassium channel opening contribute to endothelium-dependent relaxation in human internal thoracic artery?
Opening of potassium channels can cause hyperpolarization and relaxation of vascular smooth muscle cells. The aim of this work was to investigate the contribution of potassium channel activation to vasorelaxation in internal thoracic artery taken from patients undergoing coronary artery bypass graft surgery. Relaxations to carbachol and sodium nitroprusside were studied in isolated rings of int...
متن کاملEndothelium-dependent and-independent relaxation induced by resveratrol in rat superior mesenteric arteries.
Resveratrol (Res) is a specific agonist of sirtuin 1, and has many cardioprotective effects. Although Res is able to relax various vascular beds, its pharmacological properties in rat superior mesenteric arteries and the underlying mechanism are not well clarified. The aim of present study was to investigate the vasorelaxant effects of Res on rat superior mesenteric arteries and the mechanisms ...
متن کاملSecondhand tobacco smoke impairs rabbit pulmonary artery endothelium-dependent relaxation.
OBJECTIVES To determine whether secondhand smoke (SHS) induces pulmonary artery endothelial dysfunction, and whether dietary L-arginine supplementation is preventive. BACKGROUND SHS causes coronary and peripheral arterial endothelial dysfunction. METHODS The effects of L-arginine supplementation (2.25% solution) and SHS (10 weeks) on pulmonary vascular reactivity were examined in 32 rabbits...
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ژورنال
عنوان ژورنال: Acta veterinaria
سال: 2006
ISSN: 0567-8315
DOI: 10.2298/avb0603203n